Using advanced technology to solve the sensitivity of tumor radiotherapy

In tumor radiotherapy, the sensitivity of the tumor to radiation therapy is often taken into account. In popular terms, cells that are easily killed by radiation are susceptible cells, and vice versa for radiation-resistant cells. Radiation therapy for tumor effects Different tumors are divided into radiation-sensitive, medium-sensitive and radiation-resistant tumors.
The following are the same as the "
Usually in tumor radiotherapy, often taking into account the sensitivity of the tumor to radiation therapy. In popular terms, cells that are easily killed by radiation are susceptible cells, and vice versa for radiation-resistant cells. Radiation therapy for tumor effects Different tumors are divided into radiation-sensitive, medium-sensitive and radiation-resistant tumors. Usually in 5 weeks irradiation 50GY can make the tumor subsided called highly sensitive tumors, such as malignant lymphoma, small cell lung cancer; in 6-7 weeks irradiation 60-70GY can make the tumor subsided called moderate sensitive tumor , Such as nasopharyngeal carcinoma, cervical cancer; more than 70GY is still difficult to make the subside, known as insensitive tumors, such as non-small cell lung cancer, soft tissue sarcoma and so on.
The following are the same as the "
According to experts, the tumor tissue of different sources, the sensitivity of different radiation. Originated in the radiation-sensitive tissue of the tumor, more than the radiation-resistant tissue-resistant tumors on the degree of high sensitivity to radiotherapy. Such as lymphoid tissue derived from the malignant lymphoma and originated in the military pelvic tissue of the spermatidoma radiation sensitivity of the radiation is high, and originated in the gastrointestinal adenocarcinoma radiotherapy sensitivity is low.
The following are the same as the "
Different degree of tumor cell differentiation, radiotherapy sensitivity is also different. The same type of tumor, the worse the degree of differentiation, that is, the higher the degree of malignancy, the stronger the ability to proliferate, that is, the faster the more sensitive to radiotherapy. Such as grade I astrocytoma is not sensitive to radiotherapy, and Ⅱ, Ⅲ astrocytoma is relatively sensitive. But also a small number of highly malignant tumors are not sensitive to radiotherapy, such as malignant melanoma and so on.
The following are the same as the "
The tumor growth pattern also has an effect on radiotherapy sensitivity. Where the growth of the surface of the tumor, such as superficial and cauliflower type, more sensitive to radiotherapy, and deep infiltration of growth, such as invasive and ulcerative tumors, poor sensitivity.
The following are the same as the "
However, with the progress of modern radiotherapy technology, such as the emergence of gamma knife and photon knife, the tumor radiosensitivity problems, in recent years have a new understanding. As the new radiotherapy technology can be done without increasing or even reducing the normal tissue radiation injury, increase the dose of radiation and shorten the time of radiotherapy. So that the original moderately sensitive tumor becomes highly sensitive, insensitive to the tumor becomes moderately sensitive. If the total dose of 100GY or more is allowed to be irradiated for more than 70GY (2-3 weeks) in a relatively short period of time, most tumors will be completely eliminated. At this point, sensitive and insensitive is not important, non-sensitive cells are also difficult to survive. So the tumor is sensitive to radiation and insensitive, is the doctor to the amount of radiation therapy reference factors, not to determine whether the key factors of radiotherapy. In other words, even if the tumor is not sensitive, if the tumor is small, where the site allows the use of high doses, short course of treatment, the tumor can still be cured. On the contrary, when the tumor volume is too large, the radiation involved in the normal tissue range is too wide and does not allow too much exposure, even if it is sensitive to the tumor, can not get a good therapeutic effect. Therefore, the tumor is effective for radiation therapy should be the location of the tumor, size and surrounding normal tissue dose tolerance and other factors to determine, and ultimately to allow the total dose and total time to determine the radiotherapy efficacy, not to the traditional The radiotherapy is sensitive and insensitive to determine whether it can be radiotherapy.