Bone is the most common metastatic site of advanced malignant tumors. With the continuous improvement of anti-cancer therapy, advanced cancer patients continue to extend the survival time, patients with bone metastases and other skeletal complications risk also increased significantly. Bone metastases are common in breast cancer, lung cancer and other malignant tumors.
Malignant bone metastases often lead to severe bone pain and multiple bone complications, including bone-related events SREs (bone metastases due to pathological fractures, spinal cord compression, hypercalcemia, radiotherapy for the relief of bone pain, Prevention or treatment of spinal cord compression or pathological fracture of the bone surgery, etc.).
How can bone metastases be diagnosed?
(1) bone radionuclide scanning ECT: malignant tumor bone metastases screening method, the sensitivity of 62% -98%.
(2) X-ray film: is a routine method of checking bone metastases of malignant tumors, simple, inexpensive, but low sensitivity
(3) computed tomography CT: is a routine method to check the bone metastases of malignant tumors, better reality bone structure damage, sensitivity is higher than X plain film.
(4) magnetic resonance imaging MRI: sensitivity, specificity were high, showing bone marrow cavity metastases.
(5) PET-CT: in the diagnosis of bone metastases and comprehensive assessment of tumor disease has a special advantage, but the inspection costs are expensive.
(6) bone biopsy: pathology is the gold standard for the diagnosis of bone metastasis.
How to treat?
The treatment of bone metastases is mainly to relieve pain, restore function, improve the quality of life, prevent or alleviate the occurrence of SREs.
1, attention to prevention
First do the patient's mission work, warned patients to avoid sudden reversal of the spine or limbs, to avoid weight and weight, to prevent falls. If necessary, you can configure the brace and other rehabilitation tools.
2, bone metastases pain treatment
Drug analgesia can be treated according to WHO three-step analgesic treatment: mild pain selection of non-steroidal anti-inflammatory drugs. Moderate pain Select opioid analgesics such as codeine. Severe pain Select strong opioid analgesics such as morphine.
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